Methoxamine

Not to be confused with methoxetamine.
Methoxamine
Clinical data
Trade namesVasoxine, Vasoxyl, Vasylox, others
Other namesMethoxamedrine; 2,6-Dimethoxy-β-hydroxy-α-methylphenethylamine; 2,6-Dimethoxy-β-hydroxyamphetamine
AHFS/Drugs.comInternational Drug Names
Routes of
administration		Oral, injection[1]
ATC code
Pharmacokinetic data
Elimination half-life3 hours
ExcretionUrine
Identifiers
  • 2-amino-1-(2,5-dimethoxyphenyl)propan-1-ol
CAS Number
PubChem CID
IUPHAR/BPS
DrugBank
ChemSpider
UNII
KEGG
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.006.244 Edit this at Wikidata
Chemical and physical data
FormulaC11H17NO3
Molar mass211.261 g·mol−1
3D model (JSmol)
  • O(c1ccc(OC)cc1C(O)C(N)C)C
  • InChI=1S/C11H17NO3/c1-7(12)11(13)9-6-8(14-2)4-5-10(9)15-3/h4-7,11,13H,12H2,1-3H3 checkY
  • Key:WJAJPNHVVFWKKL-UHFFFAOYSA-N checkY
  (verify)

Methoxamine, sold under the brand names Vasoxine, Vasoxyl, and Vasylox among others, is a sympathomimetic medication used as an antihypotensive agent.[2][3][4][5] It has mostly or entirely been discontinued.[6]

The drug is an α1-adrenergic receptor agonist.[4][additional citation(s) needed]

  1. ^ Cite error: The named reference Drugs@FDA was invoked but never defined (see the help page).
  2. ^ Thiele RH, Nemergut EC, Lynch C (August 2011). "The physiologic implications of isolated alpha(1) adrenergic stimulation". Anesth Analg. 113 (2): 284–296. doi:10.1213/ANE.0b013e3182124c0e. PMID 21519050.
  3. ^ Elks, J. (2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer US. p. 788. ISBN 978-1-4757-2085-3. Retrieved 2024-09-01.
  4. ^ a b Cite error: The named reference IndexNominum2000 was invoked but never defined (see the help page).
  5. ^ Pazdernik TL, Kerecsen L (2007) [2003]. "5". In Goljan EF (ed.). Pharmacology. Rapid Review (Second ed.). Philadelphia, PA: Mosby-Elsevier. p. 39. ISBN 978-0-323-04550-6.
  6. ^ Cite error: The named reference Drugs.com-International was invoked but never defined (see the help page).