Methyl aminolevulinate

Methyl aminolevulinate
Clinical data
AHFS/Drugs.comMultum Consumer Information
ATC code
Identifiers
  • Methyl 5-amino-4-oxopentanoate
CAS Number
PubChem CID
DrugBank
ChemSpider
UNII
ChEMBL
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC6H11NO3
Molar mass145.158 g·mol−1
3D model (JSmol)
  • O=C(CC(N)C(=O)OC)C
  • InChI=1S/C6H11NO3/c1-4(8)3-5(7)6(9)10-2/h5H,3,7H2,1-2H3 checkY
  • Key:FLQHIIVXMKXKFT-UHFFFAOYSA-N checkY
 ☒NcheckY (what is this?)  (verify)

Methyl aminolevulinate (MAL) is a drug used as a sensitizer in photodynamic therapy. It is a prodrug that is metabolized to protoporphyrin IX. It is marketed as Metvix.

Metvix cream is applied topically and some time later the skin is illuminated with a proprietary red light (630 nm) source (medical lamp 'Aktilite') to activate the photosensitiser.

Metvix is developed by Photocure and Galderma has bought all rights to Metvix.[1]

  1. ^ "Photocure Divests Metvix to Galderma for EUR 51 Million". Archived from the original on 2011-02-07. Retrieved 2010-09-10.