Methylphosphonyl dichloride

Methylphosphonyl dichloride
Names
Preferred IUPAC name
Methylphosphonic dichloride
Other names
Methanephosphonic dichloride
Methanephosphonic acid dichloride
Methylphosphonyl dichloride
Dichloro
Identifiers
3D model (JSmol)
ChemSpider
ECHA InfoCard 100.010.578 Edit this at Wikidata
EC Number
  • 211-634-4
UN number 9206
  • InChI=1S/CH3Cl2OP/c1-5(2,3)4/h1H3
    Key: SCLFRABIDYGTAZ-UHFFFAOYSA-N
  • InChI=1/CH3Cl2OP/c1-5(2,3)4/h1H3
    Key: SCLFRABIDYGTAZ-UHFFFAOYAS
  • CP(=O)(Cl)Cl
Properties
CH3Cl2OP
Molar mass 132.91 g·mol−1
Appearance White crystalline solid
Density 1.468 g/mL at 20 °C
Melting point 28 to 34 °C (82 to 93 °F; 301 to 307 K)
Boiling point 163 °C (325 °F; 436 K)
Reacts with water
Solubility Ether, THF
Hazards
Occupational safety and health (OHS/OSH):
Main hazards
Very toxic, reacts with water
GHS labelling:
GHS05: CorrosiveGHS06: Toxic
Danger
H314, H330
P260, P264, P271, P280, P284, P301+P330+P331, P303+P361+P353, P304+P340, P305+P351+P338, P310, P320, P321, P363, P403+P233, P405, P501
Flash point >110 °C
Lethal dose or concentration (LD, LC):
26 ppm/4h by inhalation (rat)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

Methylphosphonyl dichloride (DC) or dichloro is an organophosphorus compound. It has commercial application in oligonucleotide synthesis,[1] but is most notable as being a precursor to several chemical weapons agents. It is a white crystalline solid that melts slightly above room temperature.[2]

  1. ^ Aldrich Handbook & Catalog of Fine Chemicals. Milwaukee, WI: Aldrich Chemical Company.   1994. p. 871. As cited in HSDB.
  2. ^ "SAFETY DATA SHEET Methylphosphonic dichloride". SAFETY DATA SHEET Methylphosphonic dichloride. MilliporeSigma. June 26, 2020. Retrieved April 27, 2022.