Metronomic therapy is a new type of chemotherapy in which anti-cancer drugs are administered in a lower dose than the maximum tolerated dose repetitively over a long period to treat cancers with fewer side effects. Metronomic therapy is shown to affect both tumor microenvironment and tumor cells to achieve its therapeutic effects.[1] Metronomic therapy is also cost-effective as a lower dose is used compared to conventional chemotherapy.[2] The use of metronomic therapy has been extensively investigated and can be advantageous in selected group of patients.[3] Yet, more clinical trials are necessary to generalize the method.[4]
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