Metyrapone

Metyrapone
Clinical data
Trade namesMetopirone
AHFS/Drugs.comConsumer Drug Information
Pregnancy
category
Routes of
administration
By mouth
ATC code
Pharmacokinetic data
Elimination half-life1.9 ± 0.7 hours
Identifiers
  • 2-methyl-1,2-di(pyridin-3-yl)propan-1-one
CAS Number
PubChem CID
IUPHAR/BPS
DrugBank
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.000.188 Edit this at Wikidata
Chemical and physical data
FormulaC14H14N2O
Molar mass226.279 g·mol−1
3D model (JSmol)
  • O=C(c1cccnc1)C(c2cccnc2)(C)C
  • InChI=1S/C14H14N2O/c1-14(2,12-6-4-8-16-10-12)13(17)11-5-3-7-15-9-11/h3-10H,1-2H3 checkY
  • Key:FJLBFSROUSIWMA-UHFFFAOYSA-N checkY
  (verify)

Metyrapone, sold under the brand name Metopirone, is a medication which is used in the diagnosis of adrenal insufficiency and occasionally in the treatment of Cushing's syndrome (hypercortisolism). It is part of the steroidogenesis inhibitor class of drugs.