Michael J. Krische | |
|---|---|
 Michael J. Krische in 2014 | |
| Born | 16 September 1966 Burlingame, California |
| Nationality | American |
| Alma mater | University of California, Berkeley Stanford University |
| Known for | Krische allylation |
| Scientific career | |
| Fields | Chemistry |
| Institutions | University of Texas at Austin |
| Doctoral advisor | Barry Trost |
Michael J. Krische (FRSC, FAAAS; born September 16, 1966) is an American chemist and Robert A. Welch Chair in Science at the Department of Chemistry, University of Texas at Austin. Krische has pioneered a broad, new family of catalytic C-C bond formations that occur through the addition or redistribution of hydrogen. These processes merge the characteristics of catalytic hydrogenation and carbonyl addition, contributing to a departure from the use of stoichiometric organometallic reagents in chemical synthesis.[1][2][3][4][5][6]
- ^ Ngai, Ming-Yu; Kong, Jong-Rock; Krische, Michael J.; Bickelhaupt, F. Matthias (2007). "Hydrogen-Mediated C−C Bond Formation: A Broad New Concept in Catalytic C−C Coupling1". The Journal of Organic Chemistry. 72 (4): 1063–1072. doi:10.1021/jo061895m. PMID 17288361.
- ^ Bower, John F.; Kim, In Su; Patman, Ryan L.; Krische, Michael J. (2009). "Catalytic Carbonyl Addition through Transfer Hydrogenation: A Departure from Preformed Organometallic Reagents". Angewandte Chemie International Edition. 48 (1): 34–46. doi:10.1002/anie.200802938. PMC 2775511. PMID 19040235.
- ^ Hassan, Abbas; Krische, Michael J. (2011). "Unlocking Hydrogenation for C–C Bond Formation: A Brief Overview of Enantioselective Methods". Organic Process Research & Development. 15 (6): 1236–1242. doi:10.1021/op200195m. PMC 3224080. PMID 22125398.
- ^ Roane, James; Holmes, Michael; Krische, Michael J. (2017). "Reductive C–C coupling via hydrogenation and transfer hydrogenation: Departure from stoichiometric metals in carbonyl addition". Current Opinion in Green and Sustainable Chemistry. 7: 1–5. Bibcode:2017COGSC...7....1R. doi:10.1016/j.cogsc.2017.06.006. PMC 5926236. PMID 29726550.
- ^ Ketcham, John M.; Shin, Inji; Montgomery, T. Patrick; Krische, Michael J.; Gauss, J. (2014). "Catalytic Enantioselective C—H Functionalization of Alcohols by Redox-Triggered Carbonyl Addition: Borrowing Hydrogen, Returning Carbon". Angewandte Chemie International Edition. 53 (35): 9142–9150. doi:10.1002/anie.201403873. PMC 4150357. PMID 25056771.
- ^ Kim, Seung Wook; Zhang, Wandi; Krische, Michael J. (2017). "Catalytic Enantioselective Carbonyl Allylation and Propargylation via Alcohol-Mediated Hydrogen Transfer: Merging the Chemistry of Grignard and Sabatier". Accounts of Chemical Research. 50 (9): 2371–2380. doi:10.1021/acs.accounts.7b00308. PMC 5641472. PMID 28792731.