He pioneered the development of label-free biosensors from thin optical films of porous silicon.[3] He prepared the first microparticles and nanoparticles of porous silicon,[4] and harnessed the intrinsic photoluminescence of these formulations for in vitro and in vivo imaging applications.[5] He was the first to demonstrate time-gated luminescence imaging with these nanoparticles,[6] important because time-gating suppresses tissue autofluorescence that often compromises the fidelity of fluorescence images of biological tissues. He also adapted the concept of "Smart Dust" to the field of nanotechnology: the idea that microscopic particles can be manufactured with optical, chemical, and mechanical properties that can perform sensing, signaling, and motive functions.[7][8][9][10]
^Sailor, M.J.; Link, J.R. (10 Feb 2005). "Smart Dust: nanostructured devices in a grain of sand". Chemical Communications (11): 1375–1383. doi:10.1039/b417554a. PMID15756310.
^Dovree, J.R.; Derfus, A.M.; Bhatia, S.N.; Sailor, M.J. (7 November 2004). "Manipulation of liquid droplets using amphiphilic, magnetic 1-D photonic crystal chaperones". Nature Materials. 3 (12): 896–899. doi:10.1038/nmat1253. PMID15531887. S2CID8177935.