| Sport | Football |
|---|---|
| First meeting | November 25, 1901 Eastern Illinois, 28–0 |
| Latest meeting | September 21, 2024 Illinois State, 31–7 |
| Next meeting | September 13, 2025 |
| Trophy | Mid-America Classic Trophy |
| Statistics | |
| Meetings total | 112 |
| All-time series | Illinois State leads, 60–43–9 |
| Largest victory | ISU, 48–7 (1992) |
| Longest win streak | EIU, 8 (1924–1931) |
| Current win streak | ISU, 1 (2024–present) |
The Mid-America Classic is a long-standing American college football rivalry game played in most years since 1901 between the Panthers of Eastern Illinois University and the Redbirds of Illinois State University. The 2024 season marked the 112th meeting between the two teams. Illinois State leads the series, 60–43–9.