Minute virus of mice | |
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Virus classification | |
(unranked): | Virus |
Realm: | Monodnaviria |
Kingdom: | Shotokuvirae |
Phylum: | Cossaviricota |
Class: | Quintoviricetes |
Order: | Piccovirales |
Family: | Parvoviridae |
Genus: | Protoparvovirus |
Species: | |
Virus: | Minute virus of mice
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Minute virus of mice (MVM) is the exemplar virus of the species Rodent protoparvovirus 1, in the genus Protoparvovirus[1] of the Parvoviridae family of viruses.[2] MVM exists in multiple variant forms including MVMp, which is the prototype strain that infects cells of fibroblast origin, while MVMi, the immunosuppressive strain, infects T lymphocytes.[3] MVM is a common infection in laboratory mice due to its highly contagious nature.[4] The virus can be shed from infected mice via feces and urine, but also via fomites and nasal secretions.[4] Typically there are no clinical signs of infection in adult mice, however, experimental infection can cause multiple organ damage during fetal development or shortly after birth.[4]