Mississippi Highway 388

Mississippi Highway 388
MS 388 highlighted in orange
Route information
Maintained by MDOT
Length	15.933 mi[1] (25.642 km)
Existed	c. 1957–present
Major junctions
West end	US 45 Alt. / MS 852 in Brooksville
Major intersections	US 45 in Brooksville
East end	SR 86 near Pickensville, AL
Location
Country	United States
State	Mississippi
Counties	Noxubee
Highway system
Mississippi State Highway System Interstate US State
← MS 385 → MS 389

Mississippi Highway 388 (MS 388) is a state highway in eastern Mississippi. The route starts at the intersection of U.S. Route 45 Alternate (US 45 Alt.) and MS 852 in Brooksville, and it travels east to US 45 soon after. The route intersects MS 792 near Cliftonville, and it ends at Alabama State Route 86 (SR 86) at the Alabama–Mississippi state line. MS 388 was designated around 1957, from US 45 to a point west of the state line. The route was extended to Bigbee Valley and to the state line by 1974 and 1990, respectively.