Mississippi Highway 397

Mississippi Highway 397
Route information
Maintained by MDOT
Length	33.564 mi[1] (54.016 km)
Existed	1957–present
Major junctions
South end	MS 16 near De Kalb
Major intersections	MS 21 in Preston
North end	MS 14 in Louisville
Location
Country	United States
State	Mississippi
Counties	Kemper, Winston
Highway system
Mississippi State Highway System Interstate US State
← MS 395 → MS 403

Mississippi Highway 397 (MS 397) is a 33+1⁄2-mile-long (53.9 km) state highway in eastern Mississippi. Running generally in a southeast to northwest direction, it is signed north--south traveling from the De Kalb vicinity at MS 16 to Louisville at MS 14.