State highway in Missouri
Route 215 is a highway in southern Missouri. Its northern terminus is at Route 39 south of Stockton; its southern terminus is at U.S. Route 65 between Buffalo and Springfield. Except for a short section which overlaps Route 13, it is a two-lane highway its entire length. It was originally a set of supplemental routes. In the early 2000s, US 65 was realigned and the southern terminus was extended about one mile (1.6 km) east opposite the western terminus of Route O. The highway runs more east–west than north–south, but is marked as a north–south highway.