Mittelschmerz

Mittelschmerz
Other namesOvulation pain,[1] mid-cycle pain[2]
Approximate location of abdominal pain based on potential causes
SpecialtyGynecology
SymptomsOne sided lower abdominal pain, spotting[1][2]
Usual onsetMid menstrual cycle[1]
DurationMinutes to days[1]
CausesRelated to ovulation but mechanism unclear[2]
Diagnostic methodAfter ruling out other potential causes[3]
Differential diagnosisAppendicitis, endometriosis, ovarian cyst, ectopic pregnancy, sexually transmitted infections[1][4]
PreventionBirth control pills[1]
TreatmentAcetaminophen, ibuprofen[1]
PrognosisNone serious[3]
Frequency40% of women[4]

Mittelschmerz (German: [ˈmɪtl̩ʃmɛʁt͡s] ) is a term for pain due to ovulation. It occurs mid-cycle (between days 7 and 24) and can last minutes to up to several days.[4] The pain affects one side of the lower abdomen and may be dull or sharp in nature.[1][2] Other symptoms may include spotting.[1] Often it occurs monthly and may alternate sides.[4][2]

The underlying mechanism is unclear but may involve irritation due to release of blood and fluid from the follicle or high blood levels of luteinizing hormone causing contraction of smooth muscle.[2][4][3] Diagnosis involves ruling out other potential causes such as appendicitis, endometriosis, ovarian cysts, ectopic pregnancy, and sexually transmitted infections.[1][4][3]

Treatment may involve acetaminophen or ibuprofen.[1] Birth control pills may be used for prevention.[1] It is not serious, though may reoccur.[3] Mittelschmerz affects about 20 to 40% of women.[2][4] The term is from the German for "middle pain".[3] Its presence has been used to manage fertility.[4]

  1. ^ a b c d e f g h i j k l "Ovulation pain". nhs.uk. 19 October 2017. Archived from the original on 4 July 2023. Retrieved 11 January 2024.
  2. ^ a b c d e f g Bekaert, Sarah; Bright, Phil (19 April 2018). Women's Health: Medical Masterclass Questions and Explanatory Answers, Pt. 1. 81: CRC Press. ISBN 978-1-4987-9064-2. Archived from the original on 15 January 2024. Retrieved 11 January 2024.{{cite book}}: CS1 maint: location (link)
  3. ^ a b c d e f Dolan, Brian; Holt, Lynda (4 June 2013). Accident & Emergency: Theory into Practice. Elsevier Health Sciences. p. 452. ISBN 978-0-7020-4315-4. Archived from the original on 15 January 2024. Retrieved 11 January 2024.
  4. ^ a b c d e f g h Brott, NR; Le, JK (January 2023). "Mittelschmerz". StatPearls. PMID 31747229. Archived from the original on 28 May 2021. Retrieved 11 January 2024.