Molecular breeding

Molecular breeding is the application of molecular biology tools, often in plant breeding[1][2] and animal breeding.[3][4] In the broad sense, molecular breeding can be defined as the use of genetic manipulation performed at the level of DNA to improve traits of interest in plants and animals, and it may also include genetic engineering or gene manipulation, molecular marker-assisted selection, and genomic selection.[5] More often, however, molecular breeding implies molecular marker-assisted breeding (MAB) and is defined as the application of molecular biotechnologies, specifically molecular markers, in combination with linkage maps and genomics, to alter and improve plant or animal traits on the basis of genotypic assays.[6]

The areas of molecular breeding include:

  1. ^ Voosen, P. (2009). "Molecular Breeding Makes Crops Hardier and More Nutritious Markers, knockouts and other technical advances improve breeding without modifying genes". Scientific American.
  2. ^ "Stephen P. Moose* and Rita H. Mumm (2008) Molecular Plant Breeding as the Foundation for 21st Century Crop Improvement, Plant Physiology 147:969-977".
  3. ^ Dekkers, Jack C. M.; Hospital, Frédéric (2002). "The use of molecular genetics in the improvement of agricultural populations". Nature Reviews Genetics. 3 (1): 22–32. doi:10.1038/nrg701. PMID 11823788. S2CID 32216266.
  4. ^ C.M. Dekkers, Jack (2012). "Application of Genomics Tools to Animal Breeding". Current Genomics. 13 (3): 207–212. doi:10.2174/138920212800543057. PMC 3382275. PMID 23115522.
  5. ^ Ribaut, J-M; de Vicente, Mc; Delannay, X (April 2010). "Molecular breeding in developing countries: challenges and perspectives". Current Opinion in Plant Biology. 13 (2): 213–218. doi:10.1016/j.pbi.2009.12.011. PMID 20106715.
  6. ^ Hollington, P.A.; Steele, Katherine A. (2007), "Participatory Breeding For Drought and Salt Tolerant Crops", Advances in Molecular Breeding Toward Drought and Salt Tolerant Crops, Dordrecht: Springer Netherlands, pp. 455–478, doi:10.1007/978-1-4020-5578-2_18, ISBN 978-1-4020-5577-5, retrieved 2020-10-02
  7. ^ Meuwissen, T. H. E.; Hayes, B. J.; Goddard, M. E. (2001-04-01). "Prediction of Total Genetic Value Using Genome-Wide Dense Marker Maps". Genetics. 157 (4): 1819–1829. doi:10.1093/genetics/157.4.1819. ISSN 0016-6731. PMC 1461589. PMID 11290733.
  8. ^ Jannink, Jean-Luc; Lorenz, Aaron J.; Iwata, Hiroyoshi (2010-03-01). "Genomic selection in plant breeding: from theory to practice". Briefings in Functional Genomics. 9 (2): 166–177. doi:10.1093/bfgp/elq001. ISSN 2041-2649. PMID 20156985.
  9. ^ Heffner, Elliot L.; Sorrells, Mark E.; Jannink, Jean-Luc (2009-01-01). "Genomic Selection for Crop Improvement". Crop Science. 49 (1): 1–12. doi:10.2135/cropsci2008.08.0512. ISSN 1435-0653.