Monohybrid cross

A monohybrid cross is a cross between two organisms with different variations at one genetic locus of interest.[1][2] The character(s) being studied in a monohybrid cross are governed by two or multiple variations for a single location of a gene. Then carry out such a cross, each parent is chosen to be homozygous or true breeding for a given trait (locus). When a cross satisfies the conditions for a monohybrid cross, it is usually detected by a characteristic distribution of second-generation (F2) offspring that is sometimes called the monohybrid ratio.

Figure 1: Inheritance pattern of dominant (red) and recessive (white) phenotypes when each parent (1) is homozygous for either the dominant or recessive trait. All members of the F1 generation are heterozygous and share the same dominant phenotype (2), while the F2 generation exhibits a 6:2 ratio of dominant to recessive phenotypes (3).
  1. ^ Solomon, Eldra Pearl; Linda R. Berg; Diana W. Martin (February 2004). Biology. Cengage Learning. ISBN 978-0-534-49276-2.
  2. ^ Campbell, Neil A. (2006). Biology: concepts & connections. Pearson/Benjamin Cummings. ISBN 978-0-8053-7160-4.