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The Morris water navigation task, also known as the Morris water maze (not to be confused with water maze), is a behavioral procedure mostly used with rodents. It is widely used in behavioral neuroscience to study spatial learning and memory.[1] It enables learning, memory, and spatial working to be studied with great accuracy, and can also be used to assess damage to particular cortical regions of the brain.[1][2] It is used by neuroscientists to measure the effect of neurocognitive disorders on spatial learning and possible neural treatments, to test the effect of lesions to the brain in areas concerned with memory, and to study how age influences cognitive function and spatial learning.[1][3] The task is also used as a tool to study drug-abuse, neural systems, neurotransmitters, and brain development.[4][5]
- ^ a b c D'Hooge, R; De Deyn, PP (August 2001). "Applications of the Morris water maze in the study of learning and memory". Brain Research. Brain Research Reviews. 36 (1): 60–90. doi:10.1016/S0165-0173(01)00067-4. PMID 11516773. S2CID 2651456.
- ^ Morris, RG; Garrud, P; Rawlins, JN; O'Keefe, J (24 June 1982). "Place navigation impaired in rats with hippocampal lesions". Nature. 297 (5868): 681–3. Bibcode:1982Natur.297..681M. doi:10.1038/297681a0. PMID 7088155. S2CID 4242147.
- ^ Cite error: The named reference
Sharma2010was invoked but never defined (see the help page). - ^ Cite error: The named reference
Wongwitdecha1996was invoked but never defined (see the help page). - ^ Mendez, IA; Montgomery, KS; LaSarge, CL; Simon, NW; Bizon, JL; Setlow, B (February 2008). "Long-term effects of prior cocaine exposure on Morris water maze performance". Neurobiology of Learning and Memory. 89 (2): 185–91. doi:10.1016/j.nlm.2007.08.005. PMC 2258220. PMID 17904876.