Mosharraf Hossain (Bengali: মোশাররফ হোসেন), a Bengali masculine given name of Arabic origin, may refer to:
- Mir Mosharraf Hossain (1847–1912), Bengali novelist and playwright.
- Musharraf Hussain (nawab) (1871–1966), former Education Minister of Bengal
- Sheikh Mosharraf Hossain, former member of the Bengal Legislative Assembly
- Mosharraf Hossain (Jessore politician) (1925–1974), lawyer and member of the Constituent Assembly of Bangladesh
- Sardar Mosharraf Hossain (1927–2017), Bangladeshi advocate, politician and freedom fighter
- M. H. Khan (Musharraf Husain Khan, 1932–2018), Chief of Bangladesh Navy
- Musharrof Husain Khan (born 1933), fifth vice-Chancellor of Bangladesh University of Engineering and Technology
- Mosharraf Hossain (lawyer) (1935–1999), Bangladeshi advocate, politician and freedom fighter
- A. K. M. Mosharraf Hossain (1937–2020), Bangladesh Nationalist Party politician from Mymensingh and a former state minister of energy
- Mosharraf Hossain Shahjahan (1939–2012), Bangladeshi former State Minister of Religious Affairs
- Mosharraf Hossain (Bangladesh politician, died 2014) (c. 1939–2014), former Labour Minister of Bangladesh
- Mosharraf Hossain (Netrokona politician), (c. 1942–2010), Bangladeshi politician from Netrakona
- Khandaker Mosharraf Hossain (born 1942) (born 1942), former Energy Minister of Bangladesh
- Mosharraf Hossain (politician, born 1943), engineer and former Housing Minister of Bangladesh
- Khandaker Mosharraf Hossain (born 1946) (born 1946), former Health Minister of Bangladesh
- M Musharraf Hossain Bhuiyan (born 1956), former Cabinet Secretary of Bangladesh
- Md Mosharraf Hossain Bhuiyan (born 1957), Bangladeshi ambassador to Germany and former chairman of the National Board of Revenue
- Musharraf Hussain (born 1958), British-Pakistani religious scholar
- Mosharrof Hossain (born 1978), Bangladeshi kabaddi player
- Mosharraf Hossain (cricketer) (1981–2022), Bangladeshi cricketer
- Mohammad Mosharraf Hossain, Bangladeshi doctor and freedom fighter
- Mosharraf Hossain (Bogra politician), Bangladeshi politician from Bogra
- AK Mosharraf Hossain Akand, Bangladeshi politician from Mymensingh
- Mosharraf Hossain Mongu, Bangladeshi politician from Barisal
- Mosharraf Hossain (Lakshmipur politician), Bangladeshi politician from Lakshmipur
- Mosharraf Hossain (boxer), Bangladeshi boxer