Mucin 2

MUC2
Identifiers
Aliases	MUC2, MLP, MUC-2, SMUC, mucin 2, oligomeric mucus/gel-forming
External IDs	OMIM: 158370; MGI: 1339364; HomoloGene: 136755; GeneCards: MUC2; OMA:MUC2 - orthologs
Gene location (Human)
Chr.	Chromosome 11 (human)
End	1,110,511 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	141,308,430 bp
RNA expression pattern
	Top expressed in
	mucosa of transverse colon; ; rectum; ; duodenum; ; appendix; ; epithelium of colon; ; smooth muscle tissue; ; olfactory zone of nasal mucosa; ; muscle layer of sigmoid colon; ; right coronary artery; ; urinary bladder;
	Top expressed in
	jejunum; ; colon; ; ileum; ; duodenum; ; neural layer of retina; ; urinary bladder; ; zygote; ; tail of embryo; ; embryo; ; embryo;
	More reference expression data
	n/a
Gene ontology
Molecular function	protein binding;
Cellular component	extracellular region; outer mucus layer; Golgi lumen; inner mucus layer; mucus layer; plasma membrane; collagen-containing extracellular matrix;
Biological process	O-glycan processing; maintenance of gastrointestinal epithelium; stimulatory C-type lectin receptor signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	4583
	17831
	ENSG00000198788
	ENSMUSG00000025515
	Q02817
	n/a
	NM_002457
	NM_023566
	NP_002448
	n/a
	Wikidata
View/Edit Human	View/Edit Mouse

Mucin 2, oligomeric mucus gel-forming, also known as MUC2, is a protein that in humans is encoded by the MUC2 gene.^[5]^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000198788 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000025515 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Allen A, Hutton DA, Pearson JP (July 1998). "The MUC2 gene product: a human intestinal mucin". Int. J. Biochem. Cell Biol. 30 (7): 797–801. doi:10.1016/S1357-2725(98)00028-4. PMID 9722984.
^ Rousseau K, Byrne C, Kim YS, Gum JR, Swallow DM, Toribara NW (May 2004). "The complete genomic organization of the human MUC6 and MUC2 mucin genes". Genomics. 83 (5): 936–9. doi:10.1016/j.ygeno.2003.11.003. PMID 15081123.