Muddy Creek is a 15.7-mile-long (25.3 km)[1] tributary of the Conestoga River in Lancaster County, Pennsylvania, in the United States.[2]
The tributary Little Muddy Creek joins Muddy Creek 3.7 miles (6.0 km) from the Conestoga River.[1] Muddy Creek joins the Conestoga River 7.5 miles (12.1 km) upstream from Brownstown.[1]
Muddy Creek was formerly spanned by the Red Run Covered Bridge.