Murine norovirus

Murine norovirus
Virus classification Edit this classification
(unranked): Virus
Realm: Riboviria
Kingdom: Orthornavirae
Phylum: Pisuviricota
Class: Pisoniviricetes
Order: Picornavirales
Family: Caliciviridae
Genus: Norovirus
Virus:
Murine norovirus

Murine norovirus (MNV) is a species of norovirus affecting mice. It was first identified in 2003.[1] MNV is commonly used in research to model Human norovirus[2] because the latter is difficult to grow in the laboratory. Standardized cell cultures are used in MNV propagation and the virus naturally infects mice, which allows studies in animal systems.[3]

  1. ^ Karst SM, Wobus CE, Lay M, Davidson J, Virgin HW (March 2003). "STAT1-dependent innate immunity to a Norwalk-like virus". Science. 299 (5612): 1575–8. Bibcode:2003Sci...299.1575K. doi:10.1126/science.1077905. PMID 12624267. S2CID 10044606.
  2. ^ Oka T, Stoltzfus GT, Zhu C, Jung K, Wang Q, Saif LJ (2018-02-13). "Attempts to grow human noroviruses, a sapovirus, and a bovine norovirus in vitro". PLOS ONE. 13 (2): e0178157. Bibcode:2018PLoSO..1378157O. doi:10.1371/journal.pone.0178157. PMC 5810978. PMID 29438433.
  3. ^ Vashist S, Bailey D, Putics A, Goodfellow I (July 2009). "Model systems for the study of human norovirus Biology". Future Virology. 4 (4): 353–367. doi:10.2217/fvl.09.18. PMC 3079900. PMID 21516251.