Mycobacteriophage

Mycobacteriophage ZoeJ Structural Model at Atomic Resolution[1]

A mycobacteriophage is a member of a group of bacteriophages known to have mycobacteria as host bacterial species. While originally isolated from the bacterial species Mycobacterium smegmatis and Mycobacterium tuberculosis,[2] the causative agent of tuberculosis, more than 4,200 mycobacteriophage have since been isolated from various environmental and clinical sources. 2,042 have been completely sequenced.[3] Mycobacteriophages have served as examples of viral lysogeny and of the divergent morphology and genetic arrangement characteristic of many phage types.[4]

All mycobacteriophages found thus far have had double-stranded DNA genomes and have been classified by their structure and appearance into siphoviridae or myoviridae.[5]

  1. ^ Padilla-Sanchez V (24 July 2021), Mycobacteriophage ZoeJ Structural Model at Atomic Resolution, doi:10.5281/zenodo.5132914, retrieved 24 July 2021
  2. ^ Mankiewicz E (September 1961). "Mycobacteriophages isolated from persons with tuberculous and non-tuberculous conditions". Nature. 191 (4796): 1416–1417. Bibcode:1961Natur.191.1416M. doi:10.1038/1911416b0. PMID 14469307. S2CID 4263411.
  3. ^ "Mycobacteriophage Database". Phagesdb.org. Retrieved 4 September 2017.
  4. ^ Hatfull GF (13 October 2010). "Mycobacteriophages: genes and genomes". Annual Review of Microbiology. 64 (1): 331–356. doi:10.1146/annurev.micro.112408.134233. PMID 20528690.
  5. ^ Pope WH, Jacobs-Sera D, Russell DA, Peebles CL, Al-Atrache Z, Alcoser TA, et al. (January 2011). "Expanding the diversity of mycobacteriophages: insights into genome architecture and evolution". PLOS ONE. 6 (1): e16329. Bibcode:2011PLoSO...616329P. doi:10.1371/journal.pone.0016329. PMC 3029335. PMID 21298013.