| killer cell lectin-like receptor subfamily C, member 1 | |||||||
|---|---|---|---|---|---|---|---|
| Identifiers | |||||||
| Symbol | KLRC1 | ||||||
| Alt. symbols | NKG2, NKG2-A, NKG2-B, CD159a | ||||||
| NCBI gene | 3821 | ||||||
| HGNC | 6374 | ||||||
| OMIM | 161555 | ||||||
| RefSeq | NM_007328 | ||||||
| UniProt | P26715 | ||||||
| Other data | |||||||
| Locus | Chr. 12 p13 | ||||||
| |||||||
NKG2 also known as CD159 (Cluster of Differentiation 159) is a receptor for natural killer cells (NK cells). There are 7 NKG2 types: A, B, C, D, E, F and H. NKG2D is an activating receptor on the NK cell surface. NKG2A dimerizes with CD94 to make an inhibitory receptor (CD94/NKG2).
IPH2201 is a monoclonal antibody targeted at NKG2A.[1]