Nanobacterium

"Nanobacterium"
Scientific classification
Domain:
Phylum:
Class:
Order:
[not assigned]
Family:
[not assigned]
Genus:
"Nanobacterium"

Ciftcioglu et al. 1997[1]
Species
Structures found on meteorite fragment Allan Hills 84001

Nanobacterium (/ˌnænbækˈtɪəriəm/ NAN-oh-bak-TEER-ee-əm, pl. nanobacteria /ˌnænbækˈtɪəriə/ NAN-oh-bak-TEER-ee-ə) is the unit or member name of a former proposed class of living organisms, specifically cell-walled microorganisms, now discredited, with a size much smaller than the generally accepted lower limit for life (about 200 nm for bacteria, like mycoplasma). Originally based on observed nano-scale structures in geological formations (including the Martian meteorite Allan Hills 84001), the status of nanobacteria was controversial, with some researchers suggesting they are a new class of living organism[2][3] capable of incorporating radiolabeled uridine,[4] and others attributing to them a simpler, abiotic nature.[5][6] One skeptic dubbed them "the cold fusion of microbiology", in reference to a notorious episode of supposed erroneous science.[7] The term "calcifying nanoparticles" (CNPs) has also been used as a conservative name regarding their possible status as a life form.

Research tends to agree that these structures exist, and appear to replicate in some way.[8] However, the idea that they are living entities has now largely been discarded, and the particles are instead thought to be nonliving crystallizations of minerals and organic molecules.[9]

  1. ^ Ciftcioglu N, Kuronen I, Åkerman K, Hiltunen E, Laukkanen J, Kajander EO (1997). "A new potential threat in antigen and antibody products: Nanobacteria". In Brown F, Burton D, Doherty P, Mekalanos J, Norrby E (eds.). Vaccines 97. Molecular approaches to the control of infectious diseases. New York: Cold Spring Harbor Laboratory Press. pp. 99–103. ISBN 0-87969-516-1.
  2. ^ Kajander E (2006). "Nanobacteria—propagating calcifying nanoparticles". Lett Appl Microbiol. 42 (6): 549–52. doi:10.1111/j.1472-765X.2006.01945.x. PMID 16706890. S2CID 20169194.
  3. ^ Ciftcioglu N, McKay D, Mathew G, Kajander E (2006). "Nanobacteria: fact or fiction? Characteristics, detection, and medical importance of novel self-replicating, calcifying nanoparticles". J Investig Med. 54 (7): 385–94. doi:10.2310/6650.2006.06018. hdl:2060/20060028181. PMID 17169260. S2CID 35400477.
  4. ^ Cite error: The named reference mayo1 was invoked but never defined (see the help page).
  5. ^ Cite error: The named reference Cisar was invoked but never defined (see the help page).
  6. ^ Martel J, Young JD (April 2008). "Purported nanobacteria in human blood as calcium carbonate nanoparticles". Proc. Natl. Acad. Sci. U.S.A. 105 (14): 5549–54. Bibcode:2008PNAS..105.5549M. doi:10.1073/pnas.0711744105. PMC 2291092. PMID 18385376.
  7. ^ Jack Maniloff, quoted in "The Rise and Fall of Nanobacteria", Young and Martel, Scientific American, January 2010
  8. ^ Raoult, D; Drancourt, M; Azza, S; Nappez, C; Guieu, R; Rolain, JM; Fourquet, P; Campagna, B; et al. (2008). "Nanobacteria Are Mineralo Fetuin Complexes". PLOS Pathogens. 4 (2): e41. doi:10.1371/journal.ppat.0040041. PMC 2242841. PMID 18282102.
  9. ^ "The Rise and Fall of Nanobacteria", Young and Martel, Scientific American, January 2010