Negligible senescence is a term coined by biogerontologist Caleb Finch to denote organisms that do not exhibit evidence of biological aging (senescence), such as measurable reductions in their reproductive capability, measurable functional decline, or rising death rates with age.[1] There are many species where scientists have seen no increase in mortality after maturity.[1] This may mean that the lifespan of the organism is so long that researchers' subjects have not yet lived up to the time when a measure of the species' longevity can be made. Turtles, for example, were once thought to lack senescence, but more extensive observations have found evidence of decreasing fitness with age.[2]
Study of negligibly senescent animals may provide clues that lead to better understanding of the aging process and influence theories of aging.[1][3] The phenomenon of negligible senescence in some animals is a traditional argument for attempting to achieve similar negligible senescence in humans by technological means.
- ^ a b c Finch C (1994). "Negligible Senescence". Longevity, Senescence and the Genome. Chicago, IL: . University of Chicago Press. pp. 206–247.
- ^ Cite error: The named reference
:0was invoked but never defined (see the help page). - ^ Guerin JC (June 2004). "Emerging area of aging research: long-lived animals with "negligible senescence"". Annals of the New York Academy of Sciences. 1019 (1): 518–520. Bibcode:2004NYASA1019..518G. doi:10.1196/annals.1297.096. PMID 15247078. S2CID 6418634.