| Combination of | |
|---|---|
| Polymyxin B sulfate | Antibiotic |
| Neomycin sulfate | Antibiotic |
| Bacitracin zinc | Antibiotic |
| Clinical data | |
| Trade names | Neosporin, others |
| AHFS/Drugs.com | Professional Drug Facts |
| MedlinePlus | a601098 |
| License data | |
| Routes of administration | Topical, eye drops |
| ATC code | |
| Legal status | |
| Legal status |
|
| Identifiers | |
| CAS Number | |
| ChemSpider | |
| KEGG | |
| (verify) | |
Neomycin/polymyxin B/bacitracin, also known as triple antibiotic ointment, is an antibiotic medication used to reduce the risk of infections following minor skin injuries.[1][2] It contains the three antibiotics neomycin, polymyxin B, and bacitracin.[1] It is for topical use.[3][4]
Possible side effects include itchiness and skin rash,[5] and in rare cases hearing loss.[5] It is relatively broad spectrum, being effective against both Gram-negative and Gram-positive bacteria.[2]
The combination is available over the counter in the US.[5] In 2021, it was the 376th most commonly prescribed medication in the United States, with more than 25,000 prescriptions.[6]
- ^ a b "neomycin, bacitracin, polymyxin B ointment". dailymed.nlm.nih.gov. US: National Institutes of Health. Retrieved 19 April 2019.
- ^ a b "Neomycin and polymyxin B sulfates and bacitracin zinc ophthalmic ointment" (PDF). FDA.gov. U.S. Food and Drug Administration. Retrieved 19 April 2019.
- ^ Cite error: The named reference
pmid17914912was invoked but never defined (see the help page). - ^ Zintel HA, Ma RA (October 1949). "The absorption, distribution, excretion and toxicity of bacitracin in man". The American Journal of the Medical Sciences. 218 (4): 439–445. doi:10.1097/00000441-194910000-00012. PMID 18140540. S2CID 2371497.
- ^ a b c "Neomycin, polymyxin b, and bacitracin Topical Advanced Patient Information". Drugs.com. Retrieved 19 April 2019.
- ^ "Bacitracin; Neomycin; Polymyxin B - Drug Usage Statistics". ClinCalc. Retrieved 14 January 2024.