Nephrocalcinosis

Nephrocalcinosis
Other namesAnderson-Carr kidneys
Bilateral nephrocalcinosis seen on an abdominal x-ray
SpecialtyUrology Edit this on Wikidata

Nephrocalcinosis, once known as Albright's calcinosis after Fuller Albright, is a term originally used to describe the deposition of poorly soluble calcium salts in the renal parenchyma due to hyperparathyroidism. The term nephrocalcinosis is used to describe the deposition of both calcium oxalate and calcium phosphate.[1] It may cause acute kidney injury. It is now more commonly used to describe diffuse, fine, renal parenchymal calcification in radiology.[2] It is caused by multiple different conditions and is determined by progressive kidney dysfunction. These outlines eventually come together to form a dense mass.[3] During its early stages, nephrocalcinosis is visible on x-ray, and appears as a fine granular mottling over the renal outlines. It is most commonly seen as an incidental finding with medullary sponge kidney on an abdominal x-ray. It may be severe enough to cause (as well as be caused by) renal tubular acidosis or even end stage kidney disease, due to disruption of the kidney tissue by the deposited calcium salts.

  1. ^ Sayer, John A.; Carr, Georgina; Simmons, Nicholas L. (June 2004). "Nephrocalcinosis: molecular insights into calcium precipitation within the kidney". Clinical Science. 106 (6): 549–561. doi:10.1042/CS20040048. ISSN 0143-5221. PMID 15027893.
  2. ^ "Nephrocalcinosis". eMedicine. 2003-09-09. Retrieved 2007-03-10.
  3. ^ "Albright's Nephrocalcinosis". e-radiology. Retrieved 2007-03-10.