Neurosarcoidosis

Neurosarcoidosis
Other namesBesnier-Boeck-Schaumann disease
This condition affects the cranial nerves
SpecialtyNeurology Edit this on Wikidata
Diagnostic methodBiopsy
Treatmentimmunosuppression

Neurosarcoidosis (sometimes shortened to neurosarcoid) refers to a type of sarcoidosis, a condition of unknown cause featuring granulomas in various tissues, in this type involving the central nervous system (brain and spinal cord). Neurosarcoidosis can have many manifestations, but abnormalities of the cranial nerves (a group of twelve nerves supplying the head and neck area) are the most common. It may develop acutely, subacutely, and chronically. Approximately 5–10 percent of people with sarcoidosis of other organs (e.g. lung) develop central nervous system involvement. Only 1 percent of people with sarcoidosis will have neurosarcoidosis alone without involvement of any other organs. Diagnosis can be difficult, with no test apart from biopsy achieving a high accuracy rate. Treatment is with immunosuppression.[1] The first case of sarcoidosis involving the nervous system was reported in 1905.[2][3]

  1. ^ Joseph FG, Scolding NJ (2007). "Sarcoidosis of the nervous system". Practical Neurology. 7 (4): 234–44. doi:10.1136/jnnp.2007.124263. PMID 17636138. S2CID 9658767.
  2. ^ Colover J (1948). "Sarcoidosis with involvement of the nervous system". Brain. 71 (Pt. 4): 451–75. doi:10.1093/brain/71.4.451. PMID 18124739.
  3. ^ Burns TM (August 2003). "Neurosarcoidosis". Archives of Neurology. 60 (8): 1166–8. doi:10.1001/archneur.60.8.1166. PMID 12925378.