A nevoid melanoma is a malignant neoplastic lesion of the skin. It is a type of melanoma, the most dangerous form of skin cancer. Nevoid melanomas are clinically significant because they are difficult to distinguish from a benign nevus of the skin, which requires no treatment and is common on most individuals. Nevoid morphologies represent up to 3% of all cases of melanoma.
Like other forms of melanoma, a nevoid melanoma can become a life-threatening disease through the process of metastasis, after the tumor cells invade through tissue layers and spread to other parts of the body.