Nevus sebaceus or sebaceous nevus (the first term is its Latin name, the second term is its name in English; also known as an "organoid nevus"[1]: 661 and "nevus sebaceus of Jadassohn"[2]: 773 ) is a congenital, hairless plaque that typically occurs on the face or scalp.[3] Such nevi are classified as epidermal nevi and can be present at birth, or early childhood, and affect males and females of all races equally.[4] The condition is named for an overgrowth of sebaceous glands, a relatively uncommon hamartoma, in the area of the nevus. NSJ is first described by Josef Jadassohn in 1895.[5]
Skin growths such as benign tumors and basal cell carcinoma can arise in sebaceous nevi, usually after puberty. Rarely, sebaceous nevi can give rise to sebaceous carcinoma.[6] However, the rate of such malignancies is now known to be less than had been estimated. For this reason, excision is no longer automatically recommended.[7]
^James, William; Berger, Timothy; Elston, Dirk (2005). Andrews' Diseases of the Skin: Clinical Dermatology. (10th ed.). Saunders. ISBN0-7216-2921-0.
^Freedberg, et al. (2003). Fitzpatrick's Dermatology in General Medicine. (6th ed.). McGraw-Hill. ISBN0-07-138076-0.
^Teng, Joyce M.C. Nevus sebaceousArchived 30 May 2009 at the Wayback Machine, University of Wisconsin Hospitals and Clinics Authority, last updated 16 November 2007.
^Izumi M, Tang X, Chiu CS, et al. (November 2008). "Ten cases of sebaceous carcinoma arising in nevus sebaceus". J. Dermatol. 35 (11): 704–11. doi:10.1111/j.1346-8138.2008.00550.x. PMID19120764.
^Santibanez-Gallerani A, Marshall D, Duarte AM, Melnick SJ, Thaller S (September 2003). "Should nevus sebaceus of Jadassohn in children be excised? A study of 757 cases, and literature review". J. Craniofac. Surg. 14 (5): 658–60. doi:10.1097/00001665-200309000-00010. PMID14501324.