Nitrous oxide

Nitrous oxide
Nitrous oxide's canonical forms
Ball-and-stick model with bond lengths
Space-filling model of nitrous oxide
Names
IUPAC names
Nitrous oxide[1] (not recommended)
Dinitrogen oxide[2] (alternative name)
Systematic IUPAC name
Oxodiazen-2-ium-1-ide
Other names
  • Laughing gas
  • galaxy gas
  • sweet air
  • nitrous
  • nos
  • nang
  • nitrus[citation needed]
  • protoxide of nitrogen
  • hyponitrous oxide
  • dinitrogen oxide
  • dinitrogen monoxide
Identifiers
3D model (JSmol)
8137358
ChEBI
ChEMBL
ChemSpider
DrugBank
ECHA InfoCard 100.030.017 Edit this at Wikidata
E number E942 (glazing agents, ...)
2153410
KEGG
RTECS number
  • QX1350000
UNII
UN number 1070 (compressed)
2201 (liquid)
  • InChI=1S/N2O/c1-2-3 checkY
    Key: GQPLMRYTRLFLPF-UHFFFAOYSA-N checkY
  • InChI=1/N2O/c1-2-3
  • InChI=1/N2O/c1-2-3
    Key: GQPLMRYTRLFLPF-UHFFFAOYAP
  • N#[N+][O-]
  • [N-]=[N+]=O
Properties
N
2
O
Molar mass 44.013 g/mol
Appearance colourless gas
Density 1.977 g/L (gas)
Melting point −90.86 °C (−131.55 °F; 182.29 K)
Boiling point −88.48 °C (−127.26 °F; 184.67 K)
1.5 g/L (15 °C)
Solubility soluble in alcohol, ether, sulfuric acid
log P 0.35
Vapor pressure 5150 kPa (20 °C)
−18.9·10−6 cm3/mol
1.000516 (0 °C, 101.325 kPa)
Viscosity 14.90 μPa·s[3]
Structure
linear, C∞v
0.166 D
Thermochemistry
219.96 J/(K·mol)
+82.05 kJ/mol
Pharmacology
N01AX13 (WHO)
Inhalation
Pharmacokinetics:
0.004%
5 minutes
Respiratory
Hazards
GHS labelling:
GHS03: Oxidizing
Danger
H270
P220, P244, P282, P317, P336, P370+P376, P403, P410+P403
NFPA 704 (fire diamond)
Flash point Nonflammable
Safety data sheet (SDS) Ilo.org, ICSC 0067
Related compounds
Nitric oxide
Dinitrogen trioxide
Nitrogen dioxide
Dinitrogen tetroxide
Dinitrogen pentoxide
Related compounds
Ammonium nitrate
Azide
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
☒N verify (what is checkY☒N ?)

Nitrous oxide (dinitrogen oxide or dinitrogen monoxide), commonly known as laughing gas, nitrous, factitious air, among others,[4] is a chemical compound, an oxide of nitrogen with the formula N
2
O
. At room temperature, it is a colourless non-flammable gas, and has a slightly sweet scent and taste.[4] At elevated temperatures, nitrous oxide is a powerful oxidiser similar to molecular oxygen.[4]

Nitrous oxide has significant medical uses, especially in surgery and dentistry, for its anaesthetic and pain-reducing effects,[5] and it is on the World Health Organization's List of Essential Medicines.[6] Its colloquial name, "laughing gas", coined by Humphry Davy, describes the euphoric effects upon inhaling it, which cause it to be used as a recreational drug inducing a brief "high".[5][7] When abused chronically, it may cause neurological damage through inactivation of vitamin B12. It is also used as an oxidiser in rocket propellants and motor racing fuels, and as a frothing gas for whipped cream.

Nitrous oxide is also an atmospheric pollutant, with a concentration of 333 parts per billion (ppb) in 2020, increasing at 1 ppb annually.[8][9] It is a major scavenger of stratospheric ozone, with an impact comparable to that of CFCs.[10] About 40% of human-caused emissions are from agriculture,[11][12] as nitrogen fertilisers are digested into nitrous oxide by soil micro-organisms.[13] As the third most important greenhouse gas, nitrous oxide substantially contributes to global warming.[14][15] Reduction of emissions is an important goal in the politics of climate change.[16]

  1. ^ "[Nitrous oxide]". Degruyter.com. Retrieved 24 July 2022.
  2. ^ IUPAC nomenclature of inorganic chemistry 2005. PDF, p. 317.
  3. ^ Takahashi M, Shibasaki-Kitakawa N, Yokoyama C, Takahashi S (1996). "Viscosity of Gaseous Nitrous Oxide from 298.15 K to 398.15 K at Pressures up to 25 MPa". Journal of Chemical & Engineering Data. 41 (6): 1495–1498. doi:10.1021/je960060d. ISSN 0021-9568.
  4. ^ a b c "Nitrous oxide". PubChem, US National Library of Medicine. 14 September 2024. Retrieved 20 September 2024.
  5. ^ a b Quax ML, Van Der Steenhoven TJ, Bronkhorst MW, Emmink BL (July 2020). "Frostbite injury: An unknown risk when using nitrous oxide as a party drug". Acta Chirurgica Belgica. 120 (1–4). Taylor & Francis on behalf of the Royal Belgian Society for Surgery: 140–143. doi:10.1080/00015458.2020.1782160. ISSN 0001-5458. PMID 32543291. S2CID 219702849.
  6. ^ Organization WH (2019). World Health Organization model list of essential medicines: 21st list 2019. Geneva: World Health Organization. hdl:10665/325771.
  7. ^ Turner S (30 August 2024). "Nitrous-Oxide: What is it good for?". Drug Science. Retrieved 3 October 2024.
  8. ^ Cite error: The named reference agage was invoked but never defined (see the help page).
  9. ^ Cite error: The named reference noaaesrl was invoked but never defined (see the help page).
  10. ^ Cite error: The named reference sciozo was invoked but never defined (see the help page).
  11. ^ Tian H, Xu R, Canadell JG, Thompson RL, Winiwarter W, Suntharalingam P, et al. (October 2020). "A comprehensive quantification of global nitrous oxide sources and sinks". Nature. 586 (7828): 248–256. Bibcode:2020Natur.586..248T. doi:10.1038/s41586-020-2780-0. hdl:1871.1/c74d4b68-ecf4-4c6d-890d-a1d0aaef01c9. ISSN 1476-4687. PMID 33028999. S2CID 222217027. Archived from the original on 3 December 2020. Retrieved 9 November 2020.{{cite journal}}: CS1 maint: bot: original URL status unknown (link)
  12. ^ Thompson, R. L., Lassaletta, L., Patra, P. K. (2019). "Acceleration of global N2O emissions seen from two decades of atmospheric inversion". Nat. Clim. Change. 9 (12): 993–998. Bibcode:2019NatCC...9..993T. doi:10.1038/s41558-019-0613-7. hdl:11250/2646484. S2CID 208302708.
  13. ^ "Reduce nitrous oxide emissions". Ag Matters. 13 December 2021. Retrieved 1 April 2024.
  14. ^ "Chapter 8". AR5 Climate Change 2013: The Physical Science Basis. pp. 677–678.
  15. ^ "Nitrous oxide emissions pose an increasing climate threat, study finds". phys.org. Retrieved 9 November 2020.
  16. ^ Mundschenk S (3 August 2022). "The Netherlands is showing how not to tackle climate change | The Spectator". www.spectator.co.uk. Retrieved 28 August 2022.