O'nyong'nyong virus

O'nyong'nyong virus
SpecialtyInfectious disease

The o'nyong'nyong virus (ONNV) was first isolated by researchers at the Uganda Virus Research Institute in Entebbe, Uganda, during a large outbreak of a disease in 1959 that resembled dengue fever.[1] ONNV is a togavirus (family Togaviridae), genus Alphavirus, is closely related to the chikungunya and Igbo Ora viruses, and is a member of the Semliki Forest antigenic complex.[2] The name was given to the disease by the Acholi tribe during the 1959 outbreak.[3] The name comes from the Nilotic language of Uganda and Sudan and means "weakening of the joints". The virus can infect humans and may cause disease.[4]

  1. ^ WILLIAMS, MC; WOODALL, JP; GILLETT, JD (March 1965). "O'Nyong-Nyong fever: An epidemic virus disease in East Africa". Transactions of the Royal Society of Tropical Medicine and Hygiene. 59 (2): 186–97. doi:10.1016/0035-9203(65)90080-5. PMID 14297194.
  2. ^ Brault, Aaron C.; Tesh, Robert B.; Powers, Ann M.; Weaver, Scott C. (1 February 2000). "Re-emergence of chikungunya and o'nyong-nyong viruses: evidence for distinct geographical lineages and distant evolutionary relationships". Journal of General Virology. 81 (2): 471–479. doi:10.1099/0022-1317-81-2-471. PMID 10644846.
  3. ^ Haddow, A.J.; Davies, C.W.; Walker, A.J. (November 1960). "O'nyong-nyong fever: An epidemic virus disease in East Africa 1. Introduction". Transactions of the Royal Society of Tropical Medicine and Hygiene. 54 (6): 517–522. doi:10.1016/0035-9203(60)90025-0.
  4. ^ Posey DL, O'rourke T, Roehrig JT, Lanciotti RS, Weinberg M, Maloney S (July 2005). "O'Nyong-nyong fever in West Africa". Am. J. Trop. Med. Hyg. 73 (1): 32. doi:10.4269/ajtmh.2005.73.1.0730032. PMID 16014827.