The O-Pipon-Na-Piwin Cree Nation (Cree: ᐅᐱᐴᓇᐱᐏᐣ, opiponipîwin[1]) is a First Nations band government with over 1,500 Cree registered members centred in the settlement of South Indian Lake in Manitoba, Canada. South Indian Lake is located on the southeast shores of Southern Indian Lake, about 130 km (81 mi) (by air) north of the city of Thompson.
The O-Pipon-Na-Piwin Nation's reserve lands include about 113 square kilometres (44 sq mi) of land.