ORC5

ORC5
Identifiers
Aliases	ORC5, ORC5L, ORC5P, ORC5T, PPP1R117, origin recognition complex subunit 5
External IDs	OMIM: 602331; MGI: 1347044; HomoloGene: 37636; GeneCards: ORC5; OMA:ORC5 - orthologs
Gene location (Human)
Chr.	Chromosome 7 (human)
End	104,208,047 bp
Gene location (Mouse)
Chr.	Chromosome 5 (mouse)
End	22,755,427 bp
RNA expression pattern
	Top expressed in
	secondary oocyte; ; endothelial cell; ; gonad; ; testicle; ; middle temporal gyrus; ; buccal mucosa cell; ; Brodmann area 23; ; ventricular zone; ; Achilles tendon; ; body of pancreas;
	Top expressed in
	primary oocyte; ; secondary oocyte; ; zygote; ; spermatocyte; ; epiblast; ; fetal liver hematopoietic progenitor cell; ; primitive streak; ; spermatid; ; endocardial cushion; ; embryo;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	nucleotide binding; DNA replication origin binding; protein binding; ATP binding; molecular function;
Cellular component	nuclear origin of replication recognition complex; origin recognition complex; nucleus; nucleoplasm; cytosol;
Biological process	G1 phase; DNA replication; DNA replication initiation; G1/S transition of mitotic cell cycle;
	Sources:Amigo / QuickGO
Orthologs
	5001
	26429
	ENSG00000164815
	ENSMUSG00000029012
	O43913
	Q9WUV0
	NM_001197292; NM_002553; NM_181747
	NM_011959
	NP_002544; NP_859531
	NP_036089
	Wikidata
View/Edit Human	View/Edit Mouse

Origin recognition complex subunit 5 is a protein that in humans is encoded by the ORC5 (ORC5L) gene.^[5]^[6]^[7]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000164815 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000029012 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Ishiai M, Dean FB, Okumura K, Abe M, Moon KY, Amin AA, Kagotani K, Taguchi H, Murakami Y, Hanaoka F, O'Donnell M, Hurwitz J, Eki T (Dec 1997). "Isolation of human and fission yeast homologues of the budding yeast origin recognition complex subunit ORC5: human homologue (ORC5L) maps to 7q22". Genomics. 46 (2): 294–8. doi:10.1006/geno.1997.5003. PMID 9417919.
^ Tugal T, Zou-Yang XH, Gavin K, Pappin D, Canas B, Kobayashi R, Hunt T, Stillman B (Dec 1998). "The Orc4p and Orc5p subunits of the Xenopus and human origin recognition complex are related to Orc1p and Cdc6p". The Journal of Biological Chemistry. 273 (49): 32421–9. doi:10.1074/jbc.273.49.32421. PMID 9829972.
^ "Entrez Gene: ORC5L origin recognition complex, subunit 5-like (yeast)".