OSR2 (gene)

OSR2
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2EE8
Identifiers
Aliases	OSR2, odd-skipped related transciption factor 2
External IDs	OMIM: 611297; MGI: 1930813; HomoloGene: 14200; GeneCards: OSR2; OMA:OSR2 - orthologs
Gene location (Human)
Chr.	Chromosome 8 (human)
End	98,952,104 bp
Gene location (Mouse)
Chr.	Chromosome 15 (mouse)
End	35,303,451 bp
RNA expression pattern
	Top expressed in
	palpebral conjunctiva; ; body of uterus; ; canal of the cervix; ; left uterine tube; ; seminal vesicula; ; right ovary; ; urethra; ; decidua; ; ectocervix; ; right uterine tube;
	Top expressed in
	genital tubercle; ; female external genitalia; ; uterus; ; paramesonephric duct; ; ileum; ; intestinal villus; ; vas deferens; ; eyelid; ; right kidney; ; jejunum;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	metal ion binding; protein binding; nucleic acid binding; sequence-specific DNA binding; DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II transcription regulatory region sequence-specific DNA binding;
Cellular component	nucleus;
Biological process	negative regulation of transcription by RNA polymerase II; metanephros development; mesonephros development; chondrocyte differentiation; positive regulation of cell population proliferation; positive regulation of gene expression; cell differentiation; positive regulation of bone mineralization; osteoblast proliferation; embryonic forelimb morphogenesis; embryonic hindlimb morphogenesis; embryonic skeletal limb joint morphogenesis; middle ear morphogenesis; odontogenesis; embryonic digit morphogenesis; positive regulation of transcription, DNA-templated; positive regulation of transcription by RNA polymerase II; embryonic skeletal system morphogenesis; positive regulation of epithelial cell proliferation; roof of mouth development; embryonic skeletal joint morphogenesis; head development; bone morphogenesis; eyelid development in camera-type eye; embryonic skeletal joint development; embryo development ending in birth or egg hatching; urogenital system development;
	Sources:Amigo / QuickGO
Orthologs
	116039
	107587
	ENSG00000164920
	ENSMUSG00000022330
	Q8N2R0
	Q91ZD1
	NM_001142462; NM_001286841; NM_053001; NM_001394683
	NM_054049; NM_001368665
	NP_001135934; NP_001273770; NP_443727
	NP_473390; NP_001355594
	Wikidata
View/Edit Human	View/Edit Mouse

Protein odd-skipped-related 2 is a protein that in humans is encoded by the OSR2 gene.^[5] In mice, it is involved in the development of the palate and in suppressing the formation of teeth after the eruption of adult teeth.

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000164920 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000022330 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: OSR2 odd-skipped related 2 (Drosophila)".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000164920 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000022330 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: OSR2 odd-skipped related 2 (Drosophila)".

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