OXR1

OXR1
Identifiers
AliasesOXR1, TLDC3, Nbla00307, oxidation resistance 1, CHEGDD
External IDsOMIM: 605609; MGI: 2179326; HomoloGene: 24993; GeneCards: OXR1; OMA:OXR1 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)
RefSeq (protein)
Location (UCSC)Chr 8: 106.27 – 106.75 MbChr 15: 41.31 – 41.72 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Oxidation resistance protein 1 is a protein that in humans is encoded by the OXR1 gene.[5][6] Loss of OXR1 function causes decline of the retromer complex.[7]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000164830Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000022307Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Volkert MR, Elliott NA, Housman DE (Jan 2001). "Functional genomics reveals a family of eukaryotic oxidation protection genes". Proc Natl Acad Sci U S A. 97 (26): 14530–5. doi:10.1073/pnas.260495897. PMC 18953. PMID 11114193.
  6. ^ "Entrez Gene: OXR1 oxidation resistance 1".
  7. ^ Wilson KA, Bar S, et al. (Jan 2024). "OXR1 maintains the retromer to delay brain aging under dietary restriction". Nature Communications. 15 (1): 467. Bibcode:2024NatCo..15..467W. doi:10.1038/s41467-023-44343-3. PMC 10784588. PMID 38212606.