Obelisk (biology)

An obelisk is a "viroid-like element" of a type first described in a January 2024 preprint, whose authors say that "Obelisks form their own distinct phylogenetic group",[1][2][3] as their RNA sequences, discovered by computer-aided metatranscriptomics, are not homologous with the genomic sequence of any other life form.[1] Currently, only a few methods are available for the identification of these elements from NGS data.[4]

With their relationship to other organisms being unknown, they are an example of the incertae sedis, or "enigmatic taxa".

  1. ^ a b Ivan N. Zheludev; Robert C. Edgar; Maria Jose Lopez-Galiano; Marcos de la Peña; Artem Babaian; Ami S. Bhatt; Andrew Z. Fire (21 January 2024). "Viroid-like colonists of human microbiomes". bioRxiv. doi:10.1101/2024.01.20.576352. PMC 10827157. PMID 38293115. Wikidata Q124389714.
  2. ^ Sidik, Saima (29 January 2024). "'Wildly weird' RNA bits discovered infesting the microbes in our guts". Nature. doi:10.1038/d41586-024-00266-7. PMID 38291328. S2CID 267332809. Archived from the original on 30 January 2024. Retrieved 31 January 2024.
  3. ^ Pennisi, Elizabeth (26 January 2024). "'It's insane': New viruslike entities found in human gut microbes". Science. doi:10.1126/science.znxt3dk. Archived from the original on 30 January 2024. Retrieved 31 January 2024.
  4. ^ Kremer, Frederico; de Barros, Daniele (2024). "Tormentor: An obelisk prediction and annotation pipeline". BioRxiv.org. BioRxiv. doi:10.1101/2024.05.30.596730. Retrieved 3 June 2024.