 | It has been suggested that this article be merged into Multiple system atrophy. (Discuss) Proposed since May 2024. |
| Olivopontocerebellar atrophy | |
|---|---|
| Other names | Multiple system atrophy – cerebellar subtype[1] |
 | |
| Sagittal section through right cerebellar hemisphere. The right olive has also been cut sagittally. | |
| Specialty | Neurology |
Olivopontocerebellar atrophy (OPCA) is the degeneration of neurons in specific areas of the brain – the cerebellum, pons, and inferior olivary nucleus.[2] OPCA is present in several neurodegenerative syndromes, including inherited and non-inherited forms of ataxia (such as the hereditary spinocerebellar ataxia known as Machado–Joseph disease) and multiple system atrophy (MSA), with which it is primarily associated.[2]
OPCA may also be found in the brains of individuals with prion disorders and inherited metabolic diseases. The characteristic areas of brain damage that indicate OPCA can be seen by imaging the brain using CT scans or MRI studies.[2]
The term was originally coined by Joseph Jules Dejerine and André Thomas.[3][4]
- ^ "Multiple system atrophy – cerebellar subtype: MedlinePlus Medical Encyclopedia". medlineplus.gov. Retrieved 24 May 2019.
- ^ a b c "NINDS Olivopontocerebellar Atrophy Information Page". Archived from the original on 2012-01-27. Retrieved 7 Feb 2012.
- ^ synd/1903 at Who Named It? - "Dejerine-Thomas atrophy"
- ^ J. J. Dejerine, A. Thomas. L’atrophie olivo-ponto-cérébelleuse. Nouvelle iconographie de la Salpêtrière, Paris, 1900, 13: 330-370. 1912, 25: 223-250.