One Night with Regine

One Night with Regine was a benefit concert by Filipino entertainer Regine Velasquez that took place on April 26, 2002 at the National Museum of Anthropology in Rizal Park, Manila. The charity event was organized by ABS-CBN Foundation to raise funds in support of the Bantay Bata child welfare program, which aimed to promote awareness of disadvantaged and at-risk children. The proceeds were donated to benefit the development of a children's village in Velasquez's hometown of Bulacan.

Performed in front of the National Museum, the outdoor concert featured the 85-member ensemble of the San Miguel Philharmonic Orchestra accompanied by the San Miguel Master Chorale. Ryan Cayabyab served as conductor and musical director. The set list included songs taken from Velasquez's albums, as well as covers of OPM tracks and Broadway musical themes from the West Side Story, Mamma Mia!, Sunset Boulevard, and Les Misérables.

One Night with Regine received acclaim from critics, who praised Velasquez's vocal performance and the concert's aesthetics. The show was broadcast as a television special on June 2, 2002, airing on ABS-CBN. It was awarded Best Musical Program at the 7th Asian Television Awards and Best TV Special at the 12th KBP Golden Dove Awards.