Onuf's nucleus

Onuf's nucleus
Spinal cord - grey matter (Onuf's nucleus not labeled, but region is visible)
Details
Identifiers
Latinnucleus nervi pudendi
TA98A14.1.02.139
TA26084
FMA77024
Anatomical terminology

Onuf's nucleus is a distinct group of neurons located in the ventral part (lamina IX) of the anterior horn of the sacral region of the human spinal cord involved in the maintenance of micturition and defecatory continence, as well as muscular contraction during orgasm. It contains motor neurons, and is the origin of the pudendal nerve. The sacral region of the spinal cord is the fourth segment (cervical, thoracic, and lumbar being the first three) of vertebrae in the spinal cord which consists of the vertebrae 26-30.[1] While working in New York City in 1899, Bronislaw Onuf-Onufrowicz discovered this group of unique cells and originally identified it as “Group X.” “Group X” was considered distinct by Onufrowicz because the cells were different in size from the surrounding neurons in the anterolateral group, suggesting that they were independent.[2]

  1. ^ Mannen, T (2000). "Neuropathological findings of Onuf's nucleus and its significance". Neuropathology. 20: S30–S3. doi:10.1046/j.1440-1789.2000.00298.x. PMID 11037184. S2CID 37675034.
  2. ^ Onufronwicz B (1899), "Notes on the arrangement and function of the cell groups of the sacral region of the spinal cord", J Nerv Ment Dis, 26 (8): 498–504, doi:10.1097/00005053-189908000-00006, S2CID 147602936.