The opisthonephros is the functional adult kidney in lampreys (cyclostomes), most fishes, and amphibians.[1] It is formed from the extended mesonephros along with tubules from the posterior nephric ridge.[2] The functional embryonic kidney in anamniotes is the pronephros.
Kerr coined the term ‘opisthonephros’ in 1919.[3] In 1949, Hyman wrote the opisthonephros “has used up the mesomere tissue from which in amniotes both mesonephros and metanephros come.”[3] Some accounts call opisthonephros the ‘mesonephros’, but the opisthonephros in anamniotes (lampreys, fish, and amphibians) differ considerably than the mesonephros in amniotes (reptiles, birds, and mammals).[1] Thus, the term mesonephros is usually reserved for the embryonic kidney of amniotes.[1]
The mesonephros and metanephros of amniotes are derived from different parts of the anamniote opisthonephros.[1] The metanephros is derived from the posterior part of the opisthonephros.[1] In amniotes, most of the former opisthonephros became the epididymis, and the archinephric duct became the vas deferens.[4]