Orthohepevirus A

Orthohepevirus A
TEM micrograph of "Orthohepevirus A" virions
TEM micrograph of Orthohepevirus A virions
Virus classification Edit this classification
(unranked): Virus
Realm: Riboviria
Kingdom: Orthornavirae
Phylum: Kitrinoviricota
Class: Alsuviricetes
Order: Hepelivirales
Family: Hepeviridae
Genus: Orthohepevirus
Species:
Orthohepevirus A
Synonyms[1]
  • Hepatitis E virus

The hepatitis E virus (HEV) is the causative agent of hepatitis E. It is of the species Orthohepevirus A.[a][2][1]

Globally, approximately 939 million corresponding to 1 in 8 individuals have ever experienced HEV infection. About 15–110 million individuals have recent or ongoing HEV infection.[3] The virus particle was first seen in 1983,[4] but was only molecularly cloned in 1989.[5]

  1. ^ a b c Purdy, Michael A.; et al. (June 2014). "New Classification Scheme for Hepeviridae" (PDF). International Committee on Taxonomy of Viruses (ICTV). Retrieved 1 May 2019. The species Hepatitis E virus will be renamed Orthohepevirus A, and the species Avian hepatitis E virus will be renamed Orthohepevirus B.
  2. ^ "Hepeviridae - Hepeviridae - Positive-sense RNA Viruses - ICTV". www.ictv.global.
  3. ^ Li P, Liu J, Li Y, Su J, Ma Z, Bramer WM, Cao W, de Man RA, Peppelenbosch MP, Pan Q (July 2020). "The global epidemiology of hepatitis E virus infection: A systematic review and meta-analysis". Liver International. 40 (7): 1516–1528. doi:10.1111/liv.14468. PMC 7384095. PMID 32281721.
  4. ^ Balayan MS, Andjaparidze AG, Savinskaya SS, et al. (1983). "Evidence for a virus in non-A, non-B hepatitis transmitted via the fecal-oral route". Intervirology. 20 (1): 23–31. doi:10.1159/000149370. PMID 6409836.
  5. ^ Reyes GR, Purdy MA, Kim JP, et al. (1990). "Isolation of a cDNA from the virus responsible for enterically transmitted non-A, non-B hepatitis". Science. 247 (4948): 1335–9. Bibcode:1990Sci...247.1335R. doi:10.1126/science.2107574. PMID 2107574.


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