Oscillating gene

In molecular biology, an oscillating gene is a gene that is expressed in a rhythmic pattern or in periodic cycles.[1][2] Oscillating genes are usually circadian and can be identified by periodic changes in the state of an organism. Circadian rhythms, controlled by oscillating genes, have a period of approximately 24 hours. For example, plant leaves opening and closing at different times of the day or the sleep-wake schedule of animals can all include circadian rhythms. Other periods are also possible, such as 29.5 days resulting from circalunar rhythms or 12.4 hours resulting from circatidal rhythms.[3] Oscillating genes include both core clock component genes and output genes. A core clock component gene is a gene necessary for to the pacemaker. However, an output oscillating gene, such as the AVP gene, is rhythmic but not necessary to the pacemaker.[4]

  1. ^ Tuttle, LM; Salis, H; Tomshine, J; Kaznessis, YN (2005). "Model-Driven Designs of an Oscillating Gene Network". Biophys. J. 89 (6): 3873–83. Bibcode:2005BpJ....89.3873T. doi:10.1529/biophysj.105.064204. PMC 1366954. PMID 16183880.
  2. ^ Moreno-Risueno, Miguel; Benfey, Phillip N. (2011). "Time-based patterning in development: the role of oscillating gene expression" (PDF). Landes Bioscience. 2 (3): 124–129. doi:10.4161/trns.2.3.15637. PMC 3149689. PMID 21826283.
  3. ^ Cite error: The named reference moore was invoked but never defined (see the help page).
  4. ^ Buhr, ED; Takahashi, JS (2013). "Molecular Components of the Mammalian Circadian Clock". Acta Oto-Laryngologica. Handbook of Experimental Pharmacology. 109 (5–6): 406–15. doi:10.3109/00016489009125162. PMID 2360447.