Osteolytic lesion

Osteolytic lesion at the bottom of the radius, diagnosed by a darker section that indicates a loss of bone density

An osteolytic lesion (from the Greek words for "bone" (ὀστέον), and "to unbind" (λύειν)) is a softened section of a patient's bone formed as a symptom of specific diseases, including breast cancer and multiple myeloma. This softened area appears as a hole on X-ray scans due to decreased bone density, although many other diseases are associated with this symptom.[1] Osteolytic lesions can cause pain, increased risk of bone fracture, and spinal cord compression.[2] These lesions can be treated using biophosphonates or radiation, though new solutions are being tested in clinical trials.

  1. ^ "Myeloma Bone Lesions - Lytic Bone Lesions - Bone Lesion Myeloma". Multiple Myeloma Research Foundation. Retrieved 2017-03-14.
  2. ^ Matsumoto, Toshio; Kido, Shinsuke; Inoue, Daisuke; Oshima, Takashi; Abe, Masahiro (2004). "Myeloma-Bone Interaction for the Development of Myeloma Bone Disease". Journal of Bone and Mineral Research. 19 (9): 1559–1600 – via Wiley.