Osteosclerosis

Osteosclerosis
Sclerosis of the bones of the pelvis due to prostate cancer metastases
SpecialtyMedical genetics Edit this on Wikidata

Osteosclerosis is a disorder characterized by abnormal hardening of bone and an elevation in bone density. It may predominantly affect the medullary portion and/or cortex of bone. Plain radiographs are a valuable tool for detecting and classifying osteosclerotic disorders.[1][2] It can manifest in localized or generalized osteosclerosis. Localized osteosclerosis can be caused by Legg–Calvé–Perthes disease, sickle-cell disease and osteoarthritis among others. Osteosclerosis can be classified in accordance with the causative factor into acquired and hereditary.[2][1]

  1. ^ a b EL-Sobky TA, Elsobky E, Sadek I, Elsayed SM, Khattab MF (2016). "A case of infantile osteopetrosis: The radioclinical features with literature update". Bone Rep. 4: 11–16. doi:10.1016/j.bonr.2015.11.002. PMC 4926827. PMID 28326337.{{cite journal}}: CS1 maint: multiple names: authors list (link)
  2. ^ a b Cite error: The named reference Ihde was invoked but never defined (see the help page).