Oxalobacter aliiformigenes

Oxalobacter aliiformigenes
Scientific classification Edit this classification
Domain: Bacteria
Phylum: Pseudomonadota
Class: Betaproteobacteria
Order: Burkholderiales
Family: Oxalobacteraceae
Genus: Oxalobacter
Species:
O. aliiformigenes
Binomial name
Oxalobacter aliiformigenes
Chmiel et al, 2022
Type strain
Oxalobacter aliiformigenes Va3T

Oxalobacter aliiformigenes is a Gram negative, non-spore-forming, oxalate-degrading anaerobic bacterium that was first isolated from human fecal samples.[1] O. aliiformigenes consumes oxalate as its main carbon source but is negative for indole production and negative for sulfate and nitrate reduction.[2] Cells appear rod shaped, though occasionally present as curved, and do not possess flagella.[2]

O. aliiformigenes is found in the gastrointestinal tract of humans, and is typically isolated from human feces. O. aliiformigenes is believed to have roles in mitigating calcium oxalate kidney stone disease and primary hyperoxaluria because of its unique ability to utilize oxalate as its primary carbon source and prevent absorption of oxalate.[3][4]

  1. ^ Cite error: The named reference Allison_1985 was invoked but never defined (see the help page).
  2. ^ a b Cite error: The named reference :1 was invoked but never defined (see the help page).
  3. ^ Duncan, Sylvia H.; Richardson, Anthony J.; Kaul, Poonam; Holmes, Ross P.; Allison, Milton J.; Stewart, Colin S. (2002). "Oxalobacter formigenes and its potential role in human health". Applied and Environmental Microbiology. 68 (8): 3841–3847. doi:10.1128/AEM.68.8.3841-3847.2002. ISSN 0099-2240. PMC 124017. PMID 12147479.
  4. ^ Allison, Milton J.; Cook, Herbert M.; Milne, David B.; Gallagher, Sandra; Clayman, Ralph V. (March 1986). "Oxalate Degradation by Gastrointestinal Bacteria from Humans". The Journal of Nutrition. 116 (3): 455–460. doi:10.1093/jn/116.3.455.