Oxidopamine

Oxidopamine
Names
Preferred IUPAC name
5-(2-Aminoethyl)benzene-1,2,4-triol
Identifiers
3D model (JSmol)
ChEBI
ChEMBL
ChemSpider
ECHA InfoCard 100.013.493 Edit this at Wikidata
EC Number
  • 214-842-3
KEGG
UNII
  • InChI=1S/C8H11NO3/c9-2-1-5-3-7(11)8(12)4-6(5)10/h3-4,10-12H,1-2,9H2 checkY
    Key: DIVDFFZHCJEHGG-UHFFFAOYSA-N checkY
  • InChI=1/C8H11NO3/c9-2-1-5-3-7(11)8(12)4-6(5)10/h3-4,10-12H,1-2,9H2
    Key: DIVDFFZHCJEHGG-UHFFFAOYAG
  • c1c(c(cc(c1O)O)O)CCN
Properties
C8H11NO3
Molar mass 169.18 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
☒N verify (what is checkY☒N ?)

Oxidopamine, also known as 6-hydroxydopamine (6-OHDA) or 2,4,5-trihydroxyphenethylamine, is a synthetic monoaminergic neurotoxin used by researchers to selectively destroy dopaminergic and noradrenergic neurons in the brain.

The main use for oxidopamine in scientific research is to induce Parkinsonism in laboratory animals by lesioning the dopaminergic neurons of the substantia nigra pars compacta, in order to develop and test new medicines and treatments for Parkinson's disease.