PAQR8

PAQR8
Identifiers
Aliases	PAQR8, C6orf33, LMPB1, MPRB, progestin and adipoQ receptor family member 8
External IDs	OMIM: 607780; MGI: 1921479; HomoloGene: 32702; GeneCards: PAQR8; OMA:PAQR8 - orthologs
Gene location (Human)
Chr.	Chromosome 6 (human)
End	52,407,777 bp
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)
End	21,009,874 bp
RNA expression pattern
	Top expressed in
	inferior ganglion of vagus nerve; ; globus pallidus; ; internal globus pallidus; ; subthalamic nucleus; ; external globus pallidus; ; medulla oblongata; ; pars reticulata; ; spinal cord; ; C1 segment; ; mucosa of ileum;
	Top expressed in
	deep cerebellar nuclei; ; lateral geniculate nucleus; ; cerebellar vermis; ; suprachiasmatic nucleus; ; substantia nigra; ; lobe of cerebellum; ; pontine nuclei; ; mammillary body; ; medial geniculate nucleus; ; medial vestibular nucleus;
	More reference expression data
	n/a
Gene ontology
Molecular function	steroid hormone receptor activity; steroid binding; lipid binding; signaling receptor activity;
Cellular component	integral component of membrane; membrane; Golgi apparatus; plasma membrane;
Biological process	multicellular organism development; response to steroid hormone; cell differentiation; oogenesis; steroid hormone mediated signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	85315
	74229
	ENSG00000170915
	ENSMUSG00000025931
	Q8TEZ7
	Q80ZE5
	NM_133367
	NM_028829; NM_001355122
	NP_588608
	NP_083105; NP_001342051
	Wikidata
View/Edit Human	View/Edit Mouse

Membrane progesterone receptor beta (mPRβ), or progestin and adipoQ receptor 8 (PAQR8), is a protein that in humans is encoded by the PAQR8 gene.^[5]^[6]^[7]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000170915 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000025931 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Suzuki T, Ganesh S, Agarwala KL, Morita R, Sugimoto Y, Inazawa J, Delgado-Escueta AV, Yamakawa K (Nov 2001). "A novel gene in the chromosomal region for juvenile myoclonic epilepsy on 6p12 encodes a brain-specific lysosomal membrane protein". Biochemical and Biophysical Research Communications. 288 (3): 626–36. doi:10.1006/bbrc.2001.5825. PMID 11676489.
^ Zhu Y, Rice CD, Pang Y, Pace M, Thomas P (Mar 2003). "Cloning, expression, and characterization of a membrane progestin receptor and evidence it is an intermediary in meiotic maturation of fish oocytes". Proceedings of the National Academy of Sciences of the United States of America. 100 (5): 2231–6. doi:10.1073/pnas.0336132100. PMC 151323. PMID 12574519.
^ "Entrez Gene: PAQR8 progestin and adipoQ receptor family member VIII".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000170915 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000025931 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid11676489-5] Suzuki T, Ganesh S, Agarwala KL, Morita R, Sugimoto Y, Inazawa J, Delgado-Escueta AV, Yamakawa K (Nov 2001). "A novel gene in the chromosomal region for juvenile myoclonic epilepsy on 6p12 encodes a brain-specific lysosomal membrane protein". Biochemical and Biophysical Research Communications. 288 (3): 626–36. doi:10.1006/bbrc.2001.5825. PMID 11676489.

[pmid12574519-6] Zhu Y, Rice CD, Pang Y, Pace M, Thomas P (Mar 2003). "Cloning, expression, and characterization of a membrane progestin receptor and evidence it is an intermediary in meiotic maturation of fish oocytes". Proceedings of the National Academy of Sciences of the United States of America. 100 (5): 2231–6. doi:10.1073/pnas.0336132100. PMC 151323. PMID 12574519.

[entrez-7] "Entrez Gene: PAQR8 progestin and adipoQ receptor family member VIII".

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