PLAC1

PLAC1
Identifiers
Aliases	PLAC1, CT92, OOSP2L, placenta specific 1, OOSP2B, placenta enriched 1
External IDs	OMIM: 300296; MGI: 1926287; HomoloGene: 11039; GeneCards: PLAC1; OMA:PLAC1 - orthologs
Gene location (Human) Chr. X chromosome (human)[1] Band Xq26.3 Start 134,565,838 bp[1] End 134,764,322 bp[1]
Gene location (Mouse) Chr. X chromosome (mouse)[2] Band X A5|X 29.31 cM Start 52,158,872 bp[2] End 52,328,988 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in placenta oocyte testicle secondary oocyte cartilage tissue gonad stromal cell of endometrium right testis left testis metanephros Top expressed in yolk sac decidua endocardial cushion embryo body wall blastocyst embryo abdominal wall primitive streak morula More reference expression data BioGPS More reference expression data
Gene ontology Molecular function molecular function Cellular component extracellular region cellular component Biological process multicellular organism development placenta development Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 10761 56096 Ensembl ENSG00000170965 ENSMUSG00000061082 UniProt Q9HBJ0 Q9JI83 RefSeq (mRNA) NM_021796 NM_001316887 NM_001316888 NM_001316889 NM_019538 NM_001357802 RefSeq (protein) NP_001303816 NP_001303817 NP_001303818 NP_068568 NP_062411 NP_001344731 Location (UCSC) Chr X: 134.57 – 134.76 Mb Chr X: 52.16 – 52.33 Mb PubMed search [3] [4]
Wikidata
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Placenta-specific protein 1 is a small (212 amino acid), secreted cell surface protein encoded on the X-chromosome by the PLAC1 gene.  Since its discovery in 1999, PLAC1 has been found to play a role in placental development and maintenance, several gestational disorders including preeclampsia , fetal development and a large number of cancers.