POLR1B

POLR1B
Identifiers
Aliases	POLR1B, RPA135, RPA2, Rpo1-2, polymerase (RNA) I subunit B, RNA polymerase I subunit B, A135, TCS4
External IDs	OMIM: 602000; MGI: 108014; HomoloGene: 7133; GeneCards: POLR1B; OMA:POLR1B - orthologs
Gene location (Human)
Chr.	Chromosome 2 (human)
End	112,579,818 bp
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)
End	128,968,514 bp
RNA expression pattern
	Top expressed in
	buccal mucosa cell; ; sperm; ; mucosa of paranasal sinus; ; endothelial cell; ; superficial temporal artery; ; nipple; ; ventral tegmental area; ; renal medulla; ; cardia; ; superior surface of tongue;
	Top expressed in
	Ileal epithelium; ; blastocyst; ; primitive streak; ; morula; ; epiblast; ; tail of embryo; ; yolk sac; ; ventricular zone; ; embryo; ; Paneth cell;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	transferase activity; DNA binding; nucleotidyltransferase activity; ribonucleoside binding; metal ion binding; DNA-directed 5'-3' RNA polymerase activity; protein binding; RNA polymerase I activity;
Cellular component	nucleoplasm; nucleolus; RNA polymerase I complex; nucleus; cytosol;
Biological process	termination of RNA polymerase I transcription; epigenetic maintenance of chromatin in transcription-competent conformation; transcription initiation from RNA polymerase I promoter; rRNA transcription; transcription, DNA-templated; embryo implantation; nucleologenesis; transcription elongation from RNA polymerase I promoter;
	Sources:Amigo / QuickGO
Orthologs
	84172
	20017
	ENSG00000125630
	ENSMUSG00000027395
	Q9H9Y6
	P70700
NM_019014; NM_001137604; NM_001282772; NM_001282774; NM_001282776;
	NM_001282777; NM_001282779; NM_001371969; NM_001371970; NM_001371971
	NM_009086
NP_001131076; NP_001269701; NP_001269703; NP_001269705; NP_001269706;
	NP_001269708; NP_061887; NP_001358898; NP_001358899; NP_001358900
	NP_033112
	Wikidata
View/Edit Human	View/Edit Mouse

DNA-directed RNA polymerase I subunit RPA2 is an enzyme that in humans is encoded by the POLR1B gene.^[5]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000125630 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000027395 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: POLR1B polymerase (RNA) I polypeptide B, 128kDa".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000125630 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000027395 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: POLR1B polymerase (RNA) I polypeptide B, 128kDa".

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