POLR3F

POLR3F
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2DK5, 2YU3
Identifiers
Aliases	POLR3F, RPC39, RPC6, polymerase (RNA) III subunit F, RNA polymerase III subunit F, C34
External IDs	OMIM: 617455; MGI: 1924086; HomoloGene: 4722; GeneCards: POLR3F; OMA:POLR3F - orthologs
Gene location (Human)
Chr.	Chromosome 20 (human)
End	18,484,646 bp
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)
End	144,383,915 bp
RNA expression pattern
	Top expressed in
	cerebellar hemisphere; ; right hemisphere of cerebellum; ; gonad; ; Achilles tendon; ; testicle; ; Brodmann area 9; ; ganglionic eminence; ; right frontal lobe; ; ventricular zone; ; monocyte;
	Top expressed in
	saccule; ; ectoderm; ; otic vesicle; ; otic placode; ; Rostral migratory stream; ; human fetus; ; zygote; ; tail of embryo; ; genital tubercle; ; secondary oocyte;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	DNA-directed 5'-3' RNA polymerase activity; protein binding; RNA polymerase III activity; double-stranded DNA binding; DNA binding;
Cellular component	RNA polymerase III complex; cytosol; nucleus; nucleoplasm;
Biological process	positive regulation of interferon-beta production; immune system process; defense response to virus; positive regulation of innate immune response; transcription by RNA polymerase III; innate immune response; regulation of transcription by RNA polymerase III; positive regulation of type I interferon production;
	Sources:Amigo / QuickGO
Orthologs
	10621
	70408
	ENSG00000132664
	ENSMUSG00000027427
	Q9H1D9
	Q921X6
	NM_001282526; NM_006466
	NM_029763; NM_027417
	NP_001269455; NP_006457
	NP_084039
	Wikidata
View/Edit Human	View/Edit Mouse

DNA-directed RNA polymerase III subunit RPC6 is an enzyme that in humans is encoded by the POLR3F gene.^[5]^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000132664 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000027427 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Wang Z, Roeder RG (May 1997). "Three human RNA polymerase III-specific subunits form a subcomplex with a selective function in specific transcription initiation". Genes & Development. 11 (10): 1315–26. doi:10.1101/gad.11.10.1315. PMID 9171375.
^ "Entrez Gene: POLR3F polymerase (RNA) III (DNA directed) polypeptide F, 39 kDa".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000132664 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000027427 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid9171375-5] Wang Z, Roeder RG (May 1997). "Three human RNA polymerase III-specific subunits form a subcomplex with a selective function in specific transcription initiation". Genes & Development. 11 (10): 1315–26. doi:10.1101/gad.11.10.1315. PMID 9171375.

[entrez-6] "Entrez Gene: POLR3F polymerase (RNA) III (DNA directed) polypeptide F, 39 kDa".

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